Founder's associate position Business & operations (I will not promote)

Hello everyone, I am a clinical psychologist who is trying to transition into IO psychology. After many months of applying to any job possible (Hundreds of applications) i unfortunately don't get even one interview invitation. The only jobs that always got back to me are founder's associate positions. I wonder, is it worth it? On the only posts I've found here there are many negative reviews (not helping cv, hard work, start ups usually fail) and few positive (Good for experience). What are your thoughts?